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Zix Corporation's e-Prescribing Application Helps Physicians with Vioxx Recall

DALLAS--(BUSINESS WIRE)--Oct. 4, 2004--

PocketScript(R) Enables Doctors to Quickly Identify Prescribed Users for Patient Notification

Zix Corporation (ZixCorp(R)), (Nasdaq:ZIXI), a global provider of secure e-messaging, e-prescribing, and e-transaction applications and services, today announced that its PocketScript(R) e-prescribing application is being used by physicians to notify patients taking the anti-inflammatory drug Vioxx (Rofecoxib) about the drug's recent recall status.

On Thursday, the Food and Drug Administration acknowledged the voluntary withdrawal of Vioxx -- a commonly prescribed arthritis medication manufactured by Merck & Co. -- from the market after a long-term study determined an increased risk of serious cardiovascular events among patients taking Vioxx compared to patients receiving a placebo.

Physicians using PocketScript in their practices were reminded of the recall through an alert message sent out to all users on Friday. These physicians have the advantage of immediate access to patients who have been prescribed Vioxx. The system generates several reports, including the "Patients on a Drug Report" that lists the prescribers and their patients sorted by prescriber and drug. From this report, physicians can easily alert affected patients.

Dr. Salvatore Volpe, a physician practicing in Staten Island, N.Y., used the feature to notify his patients. "We found 16 patients who had been prescribed Vioxx in the past, out of a total patient population of 2,500," said Volpe. "It was easy to use the report to quickly generate a contact list to notify these patients. This convenient feature is evidence of the value of medical office automation in improving patient safety and improving medical practice efficiency."

PocketScript also automatically checks drug-to-drug and drug-to-allergy reactions to ensure that any new medications prescribed to replace Vioxx will not interfere with current prescribed medications or conditions. Clinicians can send new medications prescribed directly to the patient's preferred pharmacy immediately for pick-up, eliminating time-consuming phone calls or follow-up clarifications due to illegibility of handwritten scripts.

"Some physicians are reluctant to move from paper scripts to e-prescribing, but this recall clearly demonstrates that an electronic solution is more than just a replacement for a pad and pen," said Dr. Daniel Z. Sands, vice president and chief medical officer for ZixCorp. "In less than a minute, a physician or staff member can find every patient that needs to be notified without combing through a single chart. They can then choose a suitable replacement medication, check for potential adverse drug interactions, and send the prescription to the pharmacy in seconds. e-Prescribing doesn't just automate the prescription process, but makes patient prescription management easier and safer, and enables quick action in events like these that affect their patients. It's just a better way to practice."

About Zix Corporation

Zix Corporation (ZixCorp(R)) is a global provider of secure e-messaging, e-prescribing, and e-transaction applications and services. ZixCorp offers a range of solutions to protect organizations from viruses, spam, and electronic attack, as well as enabling secure electronic communications, such as email encryption, e-prescribing, on-line doctor visits, and electronic lab results. ZixCorp helps organizations of any size to streamline operations, reduce risks, and leverage the efficiencies of e-messaging. For more information, visit

CONTACT: Zix Corporation, Dallas
Christa Osswald, 214-370-2175
Investor Relations:
Peter Wilensky, 214-515-7357

SOURCE: Zix Corporation